Journal: Frontiers in Physiology

Article Title: Eccentric Ergometer Training Promotes Locomotor Muscle Strength but Not Mitochondrial Adaptation in Patients with Severe Chronic Obstructive Pulmonary Disease

doi: 10.3389/fphys.2017.00114

Figure Lengend Snippet: Data obtained over 10 weeks of training in the EET (closed circles) and CET (open squares) groups. (A) Mean power output expressed in Watts per week; (B) heart rate expressed as a percentage of baseline maximal heart rate obtained at the end of the incremental cardiopulmonary exercise test; (C) Ratings of perceived exertion (RPE) using the Borg CR10 scale for leg fatigue during each training session; (D) Ratings of perceived exertion using the Borg CR10 scale for dyspnea during each training session; (E) serum CK levels at four timepoints. Weekly values for (A–D) represent the average of three exercise sessions per week per patient. Values are means ± SEM. * Significantly different compared to other group at the same time point, p < 0.05.

Article Snippet: The training protocol was set at three sessions per week of 30 min at a target intensity that was derived from our previous feasibility trial (Rocha Vieira et al., ): for the concentric group, the target cycling power was 60–80% peak workrate achieved during the baseline incremental cardiopulmonary exercise test; for the eccentric group, target intensity was equivalent to four times the power output corresponding to 60–80% peak workrate of the baseline incremental cardiopulmonary exercise test (in the concentric mode).

Techniques: